Reference: Levels of Evidence
證據等級參考
Actionable PGx (可採取行動)
The label discusses a dose adjustment, contraindication or alternate drug recommendation for patients with a particular genotype. However, the label does not strictly require or recommend genotype testing before using the drug. 標籤討論了針對特定基因型患者的劑量調整、禁忌症或替代藥物建議。然而，標籤並未嚴格要求或建議在使用藥物前進行基因型檢測。 *The criteria for Actionable PGx were updated in August 2024.*
If Tested: Adjust dose or drug if genotype is known.
若已檢測：如果基因型已知，請調整劑量或藥物。
High Priority Clinical Alerts
高優先級臨床警示
These results indicate a non-standard phenotype that likely requires dosage adjustment or alternative medication selection. 這些結果表明存在非標準表型，可能需要調整劑量或選擇替代藥物。
Important Note on Interpretation （解讀重要提示）
Genotypes are determined based on specific variant positions detected in the WGS data. "Indeterminate" results may occur when data is unphased (it is unclear which chromosome variants are on). Always consult with a pharmacist or genetic counselor before making changes to medication based on this report.
基因型是根據 WGS 數據中檢測到的特定變異位置確定的。「不確定」結果可能發生在數據未定相時（不清楚變異位於哪條染色體上）。在根據本報告更改藥物之前，請務必諮詢藥劑師或遺傳諮詢師。